Casein Protein: Uses, Dosing and Side Effects.


Casein protein is a type of protein that is found in white colored milk like yogurt, cheese, and infant formulas, as well as in a variety of dietary supplements. The most popular example of casein protein is Cow’s milk which consists of around 80%.

This protein is taken to put a stop to itchy and inflamed skin (eczema), the hypersensitivity of cow’s milk, high levels of a chemical called bilirubin in the blood of newborns (neonatal jaundice), muscle soreness after exercise, and allergies (atopic disease).

Taking the Casein protein helps to improve athletic performance, colic in infants, diabetes, exercise performance, liver disease due to alcohol consumption, cirrhosis, diarrhea, hepatitis C, acid reflux, high cholesterol, high blood pressure, infant development, weight loss, asthma, and the lung disease called chronic obstructive pulmonary disease (COPD).

Feeding infants’ casein protein formula instead of cow’s milk formula seems to reduce allergies, diarrhea, and colic. This may be explained by the lack of lactose, allergens, and other milk-based proteins in casein protein.

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Casein protein tends to increase the amount of insulin in the body. Casein protein also provides the body with all of the amino acids necessary to help build muscle. Additionally, casein protein is digested more slowly than other proteins, so it might be better at reducing appetite and increasing feelings of fullness.

Uses and Effectiveness of CASEIN PROTEIN

  • Casein protein helps to reduce the chances of an infant of 1month-6years getting eczema
  •  It reduces the risk for allergies in infants 0f 1-6years whose parents have allergic conditions
  • Formulas like Alimentum, Damira 2000, Frisolac Allergycare, and Nutramigen which contains Casein protein are safe and do not cause allergic reactions in children who have an allergic reaction to cow’s milk.
  • Also, eating hydrolyzed casein protein improves insulin and glucose levels after a meal thereby decreasing certain risk markers for type 1 diabetes.
  • Feeding an infant tends to reduce the rate of crying as well as colic for the first few days after being taken for 7days by an infant that has colics.
  • Some evidence shows that when an infant is fed with a formula containing casein protein (Nutramigen) instead of a formula containing whey protein (Enfamil) or breastmilk, it will help to reduce the chance of getting jaundice

What are the Side Effect of Casein Protein

Let’s take a look at the possible side effects of Casein protein (if any) in ADULTS, CHILDREN & INFANT, and Pregnant/Breast Feeding Women.

Casein Protein: Uses, Dosing, Side Effects | Everything you need to know

EFFECT OF CASEIN PROTEIN IN ADULTS: Most adults do not experience side effects when casein protein is taken for as long as 12 months. So, Casein protein is LIKELY SAFE for most people when taken.

EFFECT OF CASEIN PROTEIN IN INFANTS/CHILDREN: Most Infants taking casein hydrolysate formulas do not experience side effects. So I may say that its LIKELY SAFE for children and infants when taken.

EFFECT OF CASEIN PROTEIN IN Pregnancy and breast-feeding: As of the time of this publication, there is not enough reliable information about the safety of taking casein protein if you are pregnant or breastfeeding. So I advise you to avoid using casein protein when pregnant or breast feeding in order to stay on the safe side.

Dosing – How to Take Casein Protein

Casein protein is to be taken through the mouth. So, see the dozing description for both Children and Adults below;


  • For itchy and inflamed skin (eczema): Specific casein hydrolysate formulas (Nutramigen or Progestimil, Mead Johnson) for 4-6 months.
  • For allergies: A specific casein hydrolysate formula (Nutramigen, Mead Johnson) for 4-6 months.
  • For cow’s milk allergy: A variety of hydrolyzed casein formulas have been used, including Alimentum (Abbot Laboratories), Damira 2000 (Nutrition & Sante S.L.), Frisolac Allergycare (Friesland Nutrition), Nutramigen (Mead Johnson).
  • For diabetes: A specific hydrolyzed casein protein-based formula (Nutramigen, Mead Johnson) has been used when breastmilk is not available, starting at birth and lasting up to 6-8 months of age.
  • For colic in infants: Specific casein hydrolysate formulas have been used for up to 7 days. These include Alimentum (Abbot Laboratories) and Nutramigen (Mead Johnson).
  • For high levels of a chemical called bilirubin in the blood of newborns (jaundice): Casein hydrolysate formulas, including Nutramigen (Mead Johnson), for 1-3 weeks.


  • For diabetes: 0.3-0.35 grams/kg hydrolyzed casein protein with or without leucine 0.1 gram/kg. 17.6 grams hydrolyzed casein protein with or without leucine 5 grams. 12 grams hydrolyzed casein protein or 21 grams intact casein protein.

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